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Established as the standard reference for cytogenetic laboratories, this comprehensive guide to cytogenetic techniques contains chapters on peripheral blood culture, continuous cell lines, prenatal diagnosis and culture, solid tumors, fragile sites, molecular cytogenetics and much more. The manual provides an exhaustive survey of techniques for visualization and analysis of human chromosome patterns in diagnosis and research. An invaluable feature of the manual is the inclusion of over 200 protocols presented throughout the text. No other resource provides such practical “how to” instructions for cytogenetic analysis and safety and quality control.